Folic acid receptor structure folic acid, or folate, is an essential vitamin that is needed for many biological processes, including dna synthesis, dna repair and cell division. Commons is a freely licensed media file repository. Pdf structural basis for molecular recognition of folic. Folic acid c19h19n7o6 cid 5398658 structure, chemical names, physical and chemical properties, classification, patents. Folic acid 59 303 buy and find out price and availability, msds, properties of tcis high quality specialty chemicals. Structural insight into the molecular mechanism of allosteric.
The term folic acid is used to denote pteroylmonoglutamic acid or vitamin b9. Folate deficiency may cause an imbalance in dna precursors, uracil misincorporation into dna, and chromosome breakage. Structure of folic acid bound to folate receptor is solved. The chemical formula of folic acid synthetic form and the most important natural folates. Folic acid is a synthetic form of vitamin b9 thats often added to processed foods and used in supplements. Structural basis for molecular recognition of folic acid.
Aweighted 2fo fc electron density map for folic acid, shown as a grey mesh. Folates, a type of b vitamin, are involved in purine. Folic acid or folate has a molecular formula of c19h. Folate and folic acid food and agriculture organization of the. Information from its description page there is shown below.
Folate metabolism and human reproduction thieme connect. Folic acid is the synthetic form of folate, which is a naturally occurring b vitamin. Alternatively, folic acid is crucial for normal dna synthesis and repair. The top panel a denotes the structure of folic acid. Many of the research workers in folate gathered at the nih, bethesda, usa. Folic acid is a synthetic form of vitamin b9, also known as pteroylmonoglutamic acid its used in supplements and added to processed food products. Folates are folic acid compounds that occur natu rally in food. Folic acid is a composite molecule, being made up of three parts. Structure, properties, spectra, suppliers and links for. Folic acid is a water soluble vitamin of the bcomplex group. In cells and thus in food the latter are conjugated to a. As the role of folate deficiency in atherosclerotic cardiovascular disease.
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